Vinpocetine is derived from vincamine, the major indole alkaloid of the periwinkle plant. Vinpocetine has been used for many years in Europe to enhance memory and mental function by increasing neuronal firing rate. No toxic effects have been seen from vinpocetine use at levels far above therapeutic dosages.
Vinpocetine has been used in clinical practice for over 20 years in Hungary and other countries for the treatment of cerebrovascular disorders and related symptoms.
Vinpocetine can:
Improve blood supply to the brain
Increase oxygen and glucose use by the brain
Improve brain tolerance to hypoxic excitoxicity
Increase vasodilation response to hypoxia
Increase ATP levels in the brain
Reduce abnormal coagulation of blood
Raise brain levels of the neurotransmitter serotonin
Vinpocetine Research There have been quite a few studies with vinpocetine.
Dementia Researchers at the University of Surrey in Guildford, England administered vinpocetine to patients suffering from mild to moderate dementia (Hindmarch 1991). Two hundred and three patients included in a placebo-controlled, randomized double-blind trial received every day for sixteen weeks either 10 mg doses of vinpocetine three times a day, 20 mg doses of vinpocetine three times a day, or placebo three times a day. There were no clinically relevant side effects reported. Statistically significant cognitive improvements were found in favor of active treatment groups compared to placebo. The patients on 10 mg performed slightly better than those on 20 mg.
In a double blind clinical trial, vinpocetine was shown to offer significant improvement in elderly patients with chronic cerebral dysfunction. Forty-two patients received 10 mg vinpocetine three times a day for thirty days, then 5 mg three times a day for sixty days. Matching placebo tablets were given to another forty patients for the ninety-day trial period. Patients on vinpocetine scored consistently better in all cognitive evaluations. No serious side effects were reported.
Memory Twelve healthy female volunteers received pre-treatments with vinpocetine 40 mg three times a day or placebo for two days according to a randomized, double-blind crossover design. On the third day of treatment and one hour following morning dosage, subjects completed a battery of psychological tests. Memory was significantly improved following treatment with vinpocetine when compared to placebo.
Suggested Use: As a dietary supplement, take 1 or 2 capsules daily or as directed by your health care professional
Supplement Facts Serving Per Size: 1 Capsule Serving Per Container: 60 Capsules Amount Per Serving Information Ingredient Amount per serving %Daily Value Vinpocetine 20mg *
*Daily Value not established Other Ingredients: Cellulose filler, Magnesium Stearate, Vegetarian Capsules.